A new approach to targeted degradation
Reprogramming autophagy to treat disease
Reprogramming autophagy to treat disease
Autophagy is the removal of damaged components within the cell to maintain and improve health.
Autophagy creates autophagosomes that capture and degrade damaged cellular components.
Autophagy is a quality control system that maintains health and also prevents disease.
Explore the scienceOur approach is both selective and broad. We aim to maximize the potential of autophagy by enhancing degradative capacity through our PHLYT™ platform.
See our progressCasma's PHLYT™ (Phagosome-Lysosome Targeting) platform initiates target-specific autophagic degradation of new disease targets, independent of size or complexity.
Our mission is simple: We aim to reprogram autophagy to eliminate diseases that current drugs have failed to target.
Discover our storyBreakthroughs at Casma improve the lives of patients. Interested in being a part of this?
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